Synthetic Data for Biomedical Applications
Before joining SDSC, Arshjot Khehra received his MSc in Artificial Intelligence from USI Lugano, where he completed his thesis on hierarchical graph reinforcement learning. Previously, he worked for 4+ years across India and Singapore gaining data science experience in insurance, logistics, and manufacturing sectors. He also holds a BSc in Industrial Engineering from PEC Chandigarh. Over the course of his career, Arshjot worked on a wide array of projects, such as, handwritten text recognition and generation, voice matching across phone call recordings, policy lapse rate prediction for customer retention, and automated insurance claim processing.
Matthias Galipaud obtained his PhD in evolutionary biology in 2012 from the University of Burgundy in Dijon (France), and held postdoctoral positions as a mathematical biologist at the university of Bielefeld (Germany) and the university of Zurich, where he researched the evolutionary theories of aging and mate choice. In 2020, he became a data scientist, developing machine learning solutions for startups in Switzerland and Australia before joining the SDSC Innovation Team in November 2022.
Valerio started his career working for 7 years as a particle-physics researcher at CERN. There, he used state-of-the-art techniques to extract information from data, especially to search for traces of dark matter in particle collisions. Since 2016, he has worked in consulting, applying data science in several industries. First, he joined the Quant team of Ernst & Young in Geneva. Later, he created his own company, SamurAI sàrl, providing consulting services for his clients. He also has a passion for teaching very complex subjects in simple terms. That is why he particularly enjoys offering training programs to private companies and universities. Valerio joined the SDSC in Mai 2022 as a Principal Data Scientist with the mission of accompanying industrial partners and other institutions through their data science journey.
Presentation
Overview
Recently, synthetic data has enjoyed growing interest from the biomedical sector. Synthetic patient data helps in leveraging privacy issues. Augmenting datasets with synthetic records helps with increasing classification model training performance in the face of scarce health data and rare minority classes (e.g. rare diseases).
During this one-day workshop, organized by CHUV and SDSC, we will review available tools for synthetic data generation and use cases in the biomedical and pharmaceutical sectors.
Details
Target Audience
Experienced professionals, executives, and data scientists in the biomedical and pharmaceutical sectors wishing to acquire hands-on knowledge on synthetic data generation and usage.
As the workshop involves hands-on sessions, prior experience with the programming language Python is required. The workshop will be held in English.
Programme
Objectives
By the end of the day, participants will:
- Have a grasp of current available methods for synthetic tabular and image data generation.
- Have identified use cases and challenges of synthetic data in the biomedical and pharmaceutical sector.
- Have hands-on experience with generating synthetic data with python and evaluating its quality.
Agenda
09:00
Welcome coffee
09:30
Welcome & introduction
09:40
Synthetic data: How it works and where it is currently used
10:10
GANs, VAEs and diffusion: a deeper dive
10:55
Break
11:15
Applications in healthcare
11:45
Towards the use of synthetic data in biomedical applications: Evaluation of privacy and utility tradeoff
12:15
Lunch
13:15
Applications in the pharmaceutical industry
14:00
Hands-on (part 1): Understanding synthetic data generation (e.g. generating synthetic medical images for image classification)
14:50
Break
15:10
Hands-on (part 2): Understanding synthetic data evaluation (e.g., sharing survival data evaluating the utility and privacy of tabular synthetic data
16:40
Panel discussion
17:10
Concluding remarks, Apéro & Networking
Instructors
Jeremie Despraz, MS, Principal Data Scientist in Clinical AI, CHUV
Matthias Galipaud, PhD, Senior Data Scientist, SDSC, ETHZ
Beyrem Kaabachi, MS, Data Scientist in Health Data Privacy, CHUV
Arshjot Khehra, Data Scientist, SDSC ETHZ
Jean-Louis Raisaro, PhD, Tenure-Track Assistant Professor in Biomedical data science, CHUV
Alena Simalatsar, PhD, Assistant Professor, HES-SO
Practical Information
Price
Non-members: 150/pers
Ongoing collaborations with SDSC or BDSC: free
Availability & Registration
52 registered participants - Registration closed.
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Nora earned her Ph.D. in Computer Science/Bioinformatics from the University of Tübingen, where she focused on the in silico design of peptide-based vaccines using combinatorial optimization and machine learning. During her postdoctoral fellowship at Memorial Sloan Kettering Cancer Center in New York, and later as a staff scientist at the New York Genome Center, she worked on metagenomics, infectious diseases, and cancer. In 2015, Nora joined NEXUS Personalized Health Technologies at ETH Zurich where her focus shifted towards the management of clinical and biomedical research data. In May 2024, she joined the Swiss Data Science Center as Head of Biomedical Data Science.
Cyril joined the SDSC in 2022. He holds a Ph.D. in computational biology from Sorbonne University and the Institut Pasteur in Paris. There, he developed tools to detect changes in the 3D conformation of chromosomes and analyzed how it is altered during infection by bacterial pathogens. Before that, he received an MSc. in Bioinformatics from the University of Lausanne, where he worked on evolutionary genomics in insects. Over time, Cyril developed a strong interest in open and transparent scientific research. He is eager to promote good software and data management practice in research.
Stefan has a background in Biology and decided to move towards evolutionary bioinformatics for both his MSc and PhD.Over the years, he developed a passion for the entire data analysis process: from collecting data, to analyzing and presenting results. Presentations, particularly opportunities for public speaking, are activities he enjoys since he values communication a lot. In order to follow this passion and deepen his knowledge on systems to collect and manage data, he joined SDSC in 2023 as a Biomedical Data Engineer.Outside work, Stefan is an avid reader of sci-fi books (but not only!), enjoys swimming, running, and biking both competitively and casually and enjoys plenty of activities with friends, especially when beer is involved.
Daniel worked as a postdoctoral researcher on critical event prediction for the University Hospital in Zurich. In addition, Daniel has worked as a postdoctoral researcher in Lausanne, delivering algorithms for Bayesian inference in big panel data. Previously in Paris, he developed models for automated scientific discovery. He obtained a Ph.D. from the University of Edinburgh, funded by a Microsoft Research scholarship. His interest relates primarily to attacking applied biomedicine problems from different angles, frequentist statistics, Bayesian statistics, and Machine Learning.
Quentin graduated with an engineering degree in mathematics and computer science from École des Ponts ParisTech in 2019. After a 6-month experience at the Center for Data Science of the New York University working on applied Machine Learning for medical imaging, he did a PhD in Statistics at Gustave Eiffel University (Paris). During his PhD, Quentin worked on random graphs and selective inference. His recent cross-disciplinary collaborations involve applications in biology and hydrology.
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Valerio started his career working for 7 years as a particle-physics researcher at CERN. There, he used state-of-the-art techniques to extract information from data, especially to search for traces of dark matter in particle collisions. Since 2016, he has worked in consulting, applying data science in several industries. First, he joined the Quant team of Ernst & Young in Geneva. Later, he created his own company, SamurAI sàrl, providing consulting services for his clients. He also has a passion for teaching very complex subjects in simple terms. That is why he particularly enjoys offering training programs to private companies and universities. Valerio joined the SDSC in Mai 2022 as a Principal Data Scientist with the mission of accompanying industrial partners and other institutions through their data science journey.
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Carlos Vivar Ríos joined the SDSC in 2023, where he is part of the Open Research Data and Engagement Unit (ORDES). As a multidisciplinary data engineer, he brings a diverse background in biology, cognitive sciences, and bioinformatics from the University of Malaga. His multifaceted professional career spans several disciplines, including genomics at RIKEN in Yokohama, multidimensional image analysis in microscopy at the University of Lausanne (UNIL), and cellular biology modeling at INRIA in Lyon. Carlos has been involved in a variety of projects, such as analyzing astrocyte calcium dynamics, de novo sequencing Solea senegalensis, drug repurposing for Alzheimer's based on GWAS studies, conducting geospatial analysis for linguistic corpora, and assessing drought through remote sensing. He is dedicated to advancing reproducible research methods and actively supports the open science movement.
Oksana is a disruptive innovator bringing her positive energy to projects. Driven by her curiosity and can-do attitude she excels in industrial and academic contexts. Oksana earned her PhD in Life Sciences and Bioinformatics from the University of Lausanne after two MSc in Bioinformatics and in Information Systems from the University of Geneva. For more than 10 years, she has been committed to actively promoting the value of data science and advocating the best practices for reproducible and ethical research. She believes that Swiss Data Science Center is a key player in building a competitive data economy in Switzerland leveraging its innovative potential and renown commitment to quality.
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Roberto holds an M.Sc. and a Ph.D. in Particle Physics from the University of Torino, Italy. He has worked for several years in fundamental research as a senior fellow and data scientist at the CERN Experimental Physics division and on a research project supported by the Belgian National Fund for Scientific Research (FNRS). In 2018 he moved to EPFL to work on data mining and Machine Learning techniques for the built environment and renewable energies. He has started and led multiple collaborations with academic and industry partners in the energy domain. Roberto joined the SDSC in September 2021 as a Principal Data Scientist with the mission of accompanying industries, NGOs and international organizations through their data science journey.
Carl holds a Ph.D in Mathematics from École des Ponts ParisTech and Université Gustave Eiffel in Paris. He has broad interests in statistics and stochastic control, and works on reinforcement learning, generative methods and time series forecasting, with applications in various domains such as energy, finance and physics. He worked with EDF R&D and Finance des Marchés de l’Energie (FiME) laboratory on applications of machine learning to risk management, including time series generation and deep hedging. He joined the SDSC in 2022 as a senior data scientist in the academic team at École Polytechnique Fédérale de Lausanne (EPFL).
Victor joined as a Data Scientist in the SDSC Innovation team in 2023. He holds a Bachelor's degree in Mechanical Engineering (B.Eng.) from the University of Pretoria in South Africa, as well as Master's degrees in Robotics and Mechatronics (M.Sc.) and Artificial Intelligence (M.Sc.) from KU Leuven in Belgium.Prior to joining SDSC, he worked for several years as a consultant at Capgemini Engineering and as an R&D Engineer at Toyota Motor Europe. Within the Advanced Powertrain and Target Setting team at Toyota, Victor played a crucial role in the pre-development of innovative electric and fuel-cell vehicles. His responsibilities included leading the development and deployment of Natural Language Processing (NLP) tools and pipelines, data science and machine learning, building data analytics dashboards, statistical forecasting, powertrain design, optimal control system design, and strategic technical target setting. He is passionate about leveraging his combined Engineering and Data Science knowledge to solve complex problems in the industry.
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Silvia holds an MSc in Computer Science from EPFL and a PhD in Computer Science from the University of York, UK. She has been a senior research fellow at the University of Trento and later at Politecnico di Milano, Italy. Here, she had the chance to work on Marie Curie and ERC projects relating to natural language processing. From 2012 to 2019, she was a Senior Manager and NLP expert at ELCA Informatique Switzerland, whose AI department she helped create and expand. Silvia joined the Swiss Data Science Center in 2019 and is currently its Chief Transformation Officer, in charge of the team leading organizations to digital transformation.
Anna joined SDSC as a Data Scientist focusing on industry collaborations in July 2019. She completed her PhD in Bioinformatics at the University of Luxembourg, where she analysed large-scale heterogeneous datasets and leveraged multiple disciplines: Statistics, Network Analysis, and Machine Learning. Before joining SDSC, Anna worked as a Data Scientist at Deloitte Luxembourg, with a focus on computer vision and time-series analysis.Currently, Anna is a Principal Data Scientist based at the ETH Zurich office, where she leads biomedical collaborations with industry partners. Anna works on a range of projects: protein properties prediction, biomanufacturing optimization, statistical model evaluation and others.
Matthias Galipaud obtained his PhD in evolutionary biology in 2012 from the University of Burgundy in Dijon (France), and held postdoctoral positions as a mathematical biologist at the university of Bielefeld (Germany) and the university of Zurich, where he researched the evolutionary theories of aging and mate choice. In 2020, he became a data scientist, developing machine learning solutions for startups in Switzerland and Australia before joining the SDSC Innovation Team in November 2022.
Dan received an MSc in civil and environmental engineering from UC Berkeley and a Ph.D. from EPFL, where he developed models combining machine learning and geographic information systems to estimate renewable energy potentials on a large scale. After serving as a researcher/data scientist at Unisanté (Lausanne) and completing a one-year postdoc at the Quebec Artificial Intelligence Institute (Mila) in Montréal, Dan joined the SDSC Innovation team. His work has generally been focusing on crafting and tailoring machine learning methods and deep learning architectures for a variety of domains, most notably the spatio-temporal modeling and forecasting of environmental and energy related variables, as well as multiple applications in public health research.
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